Cancer treatment comes with its plethora of side effects and fatigue is the most common one cancer related fatigue. Even though fatigue is one of the highest complaints in cancer patients undergoing treatment, it went overlook for a long time. The study aimed to analyse the knowledge among fourth-year nursing students regarding the management of cancer-related fatigue at a University, Khomas Region. The research used a non-experimental, descriptive, quantitative research approach with the use of a cross-sectional questionnaire. The sampling method used was simple random sampling, of participants that meet the inclusion criteria. The study population were made up of all the 4th year nursing students enrolled under bachelor’s degree at a University which amounts to approximately 73 research participants. The results demonstrated a good understanding on the knowledge of Cancer related fatigue. However, the study also demonstrated that the students’ level of knowledge regarding its management diminished in comparison. The findings of the study call for different strategies to be created to improve the knowledge of students on the management of CRF.
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