Background: The CVD mortality rate is particularly high in sub-Saharan Africa, estimated at around 350 per 100,000 population. This is higher than the global average, estimated at 286 per 100,000 population. People in sub-Saharan Africa who have poorly controlled hypertension are significantly more vulnerable to adverse cardiovascular disease events than people in other parts of the world. This study aims to identify the determinants of cardiovascular complications. Methods and Materials: Articles were retrieved from PubMed, Scopus, PsycINFO, and goggle scholar databases for this analysis. We assessed methodological quality using the Newcastle-Ottawa Scale. An inverse-variance-weighted random-effects model meta-analysis was performed to estimate the pooled odds ratio (OR) and its 95% confidence interval (CI) for determinants. The I2 test statistic was used to check between-study heterogeneity. A p-value of less than 0.05 used to declare Statical significance. Results: Six studies comprising of 2, cross-sectional studies, 3 cohort and 1 case-control studies with a good methodological quality included in this study. Most studies were conducted in Amhara region and published from 201
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