Digital health literacy (DHL) is the ability to identify, understand, and use health information from digital sources. DHL may differ among individuals due to many factors. Therefore, this cross-sectional study investigated DHL and its associated factors among 1065 vocational college medical students in Sichuan, China, after the COVID-19 pandemic. Their demographic data were collected using a DHL questionnaire, and their health information seeking was rated. Multivariate logistic regression was used to evaluate how different factors influenced DHL. The participants had a median age of 19 years, and 82.90% were female. Among the participants, 52.26% had high DHL. Participants’ DHL was significantly influenced by age (adjusted odds ratio [AOR] = 0.83, p = 0.037), year of study (sophomore [AOR = 2.68, p < 0.001], junior [AOR = 1.82, p < 0.001]), major (nursing [AOR = 0.63, p = 0.006], rehabilitation [AOR = 0.64, p = 0.023], medicine and food or education and sports [AOR = 0.60, p < 0.001]), having had a family member or friend infected with COVID-19 (AOR = 1.64, p = 0.022), health education (AOR = 2.00, p = 0.002 ), and health information seeking (AOR = 2.33, p < 0.001). O
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