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Orbital Adenoid Cystic Carcinoma with R1 Margins – a Rare Case Managed by Precision-Guided Postoperative Radiotherapy

, Fatima-Ezzahra Alouan, Nouhaila Tnifasse, , Marwa Biyoud, · Journal of Medical and Radiation Oncology · 2025

Adenoid cystic carcinoma (ACC) is a rare malignant tumor that primarily affects the salivary glands, with orbital involvement being exceptionally uncommon. We report the case of a 76-year-old patient who presented with progressive left-sided proptosis and intermittent diplopia. Imaging, along with histopathological and immunohistochemical analyses, confirmed a trabecular-pattern ACC with perineural invasion and R1 resection status.

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