Rare case of Marchiafava Bignami Disease (MBD)

We report a case of a 45-year-old patient with a history of severe alcoholism who presented to the emergency department an impaired unconscious and weakness with upper and lower limbs. The patient was referred to our department for an MRI investigation. MRI showed abnormalities signal in the corpus callosum. The disease is due to a deficiency of each type of vitamin B, can be the result of necrosis and demyelination of the corpus callosum and later involves the genu and splenium. Keywords: Marchiafava Bignami Disease; Corpus Callosum; MRI.