The impact of immunotherapy in the treatment of solid tumors. What we found under 2021 Christmas tree

The treatment of solid tumors sees an increasing use of immune checkpoint inhibitors (anti PD-1/PDL-1, anti CTLA-4). The new drug combinations have revolutionized the treatment of different types of cancer, from melanoma to chest neoplasms, renal and esophageal cancer. All of these different diseases have one common denominator: the immune system. Only the immune system, properly stimulated, can attack and destroy different types of cancer, as if they were an infection. This review describes the most important milestones achieved in 2021 by combination treatment with immune checkpoint inhibitors.