Background: Patients who cannot afford more expensive prosthetic restorations, such as implant-supported fixed prostheses, prefer removable dentures. Removable dentures have been manufactured with different types of acrylics, including conventional polymer polymethyl methacrylate (PMMA) and the popular nowadays three–dimensional(3D) printed resins. Water sorption and water solubility often occur because these prosthetic restorations are constantly immersed in saliva and always have interactions with oral fluids. Review results: Alternating processes of imbibition and drying of acrylics lead to internal stresses and fatigue. As a result, dental resins undergo significant dimensional changes. The water diffuses into the dental resin and inflicts a gradual expansion and volume increase, which may cause aging of the material and discomfort during masticatory function. Denture base resins have low water solubility, which results from the leaching out of unreacted monomer and soluble additives into the oral cavity. This is an undesired property and may cause soft tissue reactions. Conclusion: The affinity of dental resins for water degrades their mechanical and physical properties and ca
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