Oncology patients whose are diagnosed with hypercalcemia malignant and related events associated with bone metastases and they are prescribed with antiresorptives such as bisphosphonates, denosumab or antiangiogenics drugs. Those patients could be affected with MRONJ [Medication Related Osteonecrosis of the Jaw] expressed in their different Stages: Stage 0, Stage 1, Stage 2, Stage 3. Most of them attend your dental citation on Stage 3 when MRONJ caused irreversible pain as pathological fractures, anesthesia of the lower dental nerve, bucco-sinus o bucco nasal communication, skin fistulas vaguely in maxilla or jaw. The objective of the authors is developing a clinical oncology case report with a chronical buccal sinusal communication.
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