Captopril and Hydrochlorothiazide: Insights on Pharmacology and Analytical Chemistry Profile

Many categories of drugs are used today for hypertension such as captopril which belongs to ACE inhibitors family and hydrochlorothiazide which consider a diuretic drug.In this literature review, we will focus on their pharmacological effect as well as most of the recent reported analytical methods that have been established for their determination in their pure form, combination form with other medications, combined form with its metabolites, and in biological materials.