Introduction: Chronic kidney disease (CKD) represents a distinct risk factor by itself for the development of coronary artery disease (CAD). Notably, CAD stands as the primary driver of both sickness and death among individuals diagnosed with CKD. Furthermore, individuals with CKD tend to experience worse outcomes when it comes to CAD. In addition to conventional risk factors, numerous factors associated with uremia, including inflammation, oxidative stress, endothelial dysfunction, coronary artery calcification, elevated homocysteine levels, and the use of immunosuppressants, have been linked to an increased risk of accelerated atherosclerosis. Objective and method: In this study, we aim to assess the differential effect of renal impairment across the spectrum of patients with acute coronary syndrom. We conducted this study in the intensive care unit of cardiology in the Military Teaching Hospital of Rabat. Results: A total of 318 patients were included in the study. The average age was 63.8 +/- 9.41 years and 77% (244/318) were male. Normal kidney function was reported in 72.8% (220/318) of patients. Of the 318 included patients, 121(38.3%) were presented with STEMI, 154 (48.7
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