AbstractDown Syndrome (DS) is one the most prevalent genetic disorder. This genetic disorder has physical and mental features including musculoskeletal (e.g. incorrect swallowing pattern), nervous (e.g. anxiety), and dental problems. Maintaining oral health is very important for these kinds of patients. Oral health or dental problems related to DS are localized or generalized periodontitis, mandibular prognatisma, underdeveloped maxilla, caries lesions, delayed eruptions, and oligodontia. Because of dental-oral part is the first part of the digestive system, there is need for orthodontic treatment maintaining better occlusion and mastication. In this case report, orthopedic, orthodontic, periodontal, prosthetic, and conservative dental treatments of a DS patient were presented. These kinds of patients should not be excluded from the dentistry patient population.
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