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HYPERURICEMIA IN PSORIATIC ARTHRITIS: PREVALENCE AND ASSOCIATED FACTORS

, Tania Gudu, , Alexandra Peltea, , · Romanian Journal of Rheumatology · 2017

Hyperuricemia is frequent in psoriatic arthritis (PsA) and it seems to be related to metabolic syndrome rather than extensive psoriatic skin disease. The objectives of this study were to evaluate the prevalence of hyperuricemia in PsA patients and to identify the associ-ated factors. Design: cross-sectional study, including consecutive, unselected, adult PsA patients. Data collection: demographic variables (age, gender, disease duration), clinical variables (affected joints, current moderate/severe psoriasis, nail disease, axial involvement, enthesi-tis, dactylitis), laboratory variables (acute phase reactants), treatment-related variables (non-steroidal anti-inflammatory drugs, corticosteroids, synthetic and biologic disease modifying drugs) and comorbidities. Hyperuricemia was defined as uric acid level above 6.8 mg/dl. Statistical analysis: the factors that were potentially associated with hyperuricemia were assessed by uni- and multivariate logistic regression. In all, 120 PsA patients were included in the study: 69 (57.5%) women, mean age±standard deviation 54±11.8 years, mean disease duration 7±7.4 years; 24 (20%) had moderate/severe psoriasis and 30 (25%) were taking a biolo

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