Mild cognitive impairment in multiple sclerosis

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system, including the brain, spinal cord, and optic nerves. Symptoms vary from muscle weakness to vision loss and tend to worsen during flares and improve during periods of remission. Psychiatric symptoms are common in people with MS, impacting quality of life and some features of the disease (fatigue, sleep, disability, adherence to disease-modifying drugs). The main psychiatric manifestations of MS include depressive, bipolar, anxiety, schizophrenic, and obsessive–compulsive syndromes. We present the case of a 46-year-old female patient who came to our clinic with disorientation to time and space, impaired recent and recall memory, auditory hallucinations, sad mood, irritability, and slightly decreased appetite.