Migraine is a common neurological disease characterized by severe, recurrent episodes of throbbing, unilateral, headache. Non-pharmacologic migraine treatment refers to the patient behavioral modification in order to avoid trigger. Current therapies in migraine attack treatment are non-specific drugs (non-steroidal anti-inflammatory drugs, aspirin, antiemetics) and specific antimigraine drugs (ergot alkaloids, serotonin 5-HT1B/1D receptor agonists – triptans). For migraine prophylaxis are recommended beta-blockers (metoprolol, propranolol), calcium channel blockers (flunarizine), antiepileptic drugs (valproic acid, topiramate), antidepressants (amitriptilyne, fluoxetine).
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