Objectives: This study aimed to evaluate the masking ability of different thicknesses of advanced lithium disilicate (ALDS) ceramic used for implant-supported crowns compared to conventional lithium disilicate (LDS) and to assess the influence of their combination with various implant abutment materials. Methods: Two types of high-translucency computer-aided design/computer-aided manufacturing (CAD/CAM) glass–ceramics in shade A2 were tested: IPS e.max CAD (LDS) and CEREC Tessera (ALDS). Each material was sectioned into four thicknesses (n = 8 per group). Four implant abutments were evaluated: titanium (Ti), yellow-anodized titanium (TiY), pink-anodized titanium (TiP), and white zirconia (Zir). The translucency parameter (TP00) and color difference (ΔE00) between the glass–ceramic and abutment were calculated using the CIEDE2000 formula. Results: Significant differences were observed between 1.0 mm and 2.5 mm thicknesses in all groups except for ALDS on TiY. Both glass–ceramics on TiY and TiP showed lower ΔE00 values than those on Ti, except for 2.0 mm and 2.5 mm ALDS. Additionally, their ΔE00 values were lower than those on Zir. Clinically acceptable ΔE00 values occurred for 2.5 m
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