Achieving urban economic resilience is a critical objective for sustainable development in the face of external shocks. Public health expenditure plays a pivotal role in enhancing urban economic resilience by improving health outcomes, optimizing resource allocation, and strengthening economic capacity to withstand risks. However, the mechanisms through which public health expenditure influences resilience, as well as its regional variations, remain underexplored. This study utilizes panel data from 284 cities in China spanning from 2008 to 2021, constructing an econometric model that incorporates mediating variables such as technological innovation and per capita GDP, to assess both the direct and indirect effects of public health expenditure on urban economic resilience. Additionally, spatial econometric models are employed to further analyze the spatial spillover effects of public health expenditure. The findings reveal that public health expenditure significantly enhances urban economic resilience, with technological innovation and per capita GDP serving as key mediating pathways. Regional analysis shows that the impact is most pronounced in eastern cities, followed by central
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