Objectives:This study aims to analyze and summarize the epidemic characteristics of coronavirus disease 2019 (COVID-19), and the public heath interventions in Shenzhen from 1 January 2022 to 4 April 2022, hoping to provide useful reference for resurgence.MethodsData were extracted from the website of Shenzhen Municipal Health Commission from 1 January 2022 to 4 April 2022. The number of new indigenous patients, imported patients, symptomatic and asymptomatic patients, age, gender, regional distribution, screening routes, and clinical subtype were analyzed. The public health interventions were summarized and described.ResultsThere have been 1,215 new indigenous cases and 1,447 imported cases in Shenzhen from 1 January 2022 to 4 April 2022. The age group of the indigenous cases range from 2 months to 92 years. The median age was 35.0. The male-to-female ratio was 1.13 (623:551). The number of symptomatic and asymptomatic patients were 930 (76.5%) and 285 (23.5%), respectively, without death. Shenzhen has experienced three outbreaks. Futian District has the large proportion of confirmed cases (55.8%), followed by Nanshan (13.5%), and Baoan District (13.5%). The indigenous confirmed ca
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