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Pulmonary embolism incidence among patient admitted under psychiatry department: a case-control study

Wanling Zhang, Dhirendra Paudel, Rui Shi, Junwei Yang, Jingwen Liu, Yanbin Jia · Frontiers in Psychiatry · 2024

BackgroundPulmonary embolism (PE) is a serious and potentially life-threatening condition that requires prompt diagnosis and treatment. Identifying risk factors and diagnostic markers can aid in the early detection and management of this condition.MethodsThis case-control study examined 10,077 patients admitted to Shenzhen Kangning Hospital’s psychiatry facility in 2020. Among these, 65 patients were diagnosed with PE, including 50 new cases. After survival sampling for controls and age-and-gender matching, the study included 41 new PE cases and 41 age-and-gender-matched controls. Data on demographics, comorbidities, and medication use were extracted from electronic records. Conditional logistic regression analyses were performed to determine the association between each predictor and PE risk. Additionally, the sensitivity and specificity of the d-dimer diagnostic tool were assessed.ResultsIn univariable conditional logistic regression, active alcoholism was associated with a higher PE risk (OR=3.675, 95% CI 1.02–13.14, P=0.046). A history of physical restraint (OR=4.33, 95% CI 1.24–15.21, P=0.022) and chemical restraint (OR 4.67, 95% CI 1.34–16.24, p=0.015) also increased PE risk,

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