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The Evolving COVID-19 Landscape: Role of Post-exposure Prophylaxis

American Medical Journal Microbiology and Infectious Diseases · 2025

This infographic reviews the persistent burden of COVID-19 in vulnerable populations and the clinical rationale for early post-exposure prophylaxis (PEP). It outlines why vaccines alone may not provide full protection, the high transmissibility of Omicron sublineages, and how timely PEP interventions may help reduce viral load, household spread, and severe outcomes in high-risk groups.

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