Suzuki-Miyaura, Sonogashira cross-coupling and CuACC reactions suite for the access to a large macrocycle with m,m’-terphenyl motif

The access to a large semirigid macrocycle exhibiting two m,m’-terphenyl units was carried out by a suite of Suzuki-Miyaura, Sonogashira cross-coupling and CuAAC (“click”) reactions. The target macrocycle exhibits two triazole and two ester protected carboxyl units of great use for the development of further applications.