Glucometer readings are not only affected by the intrinsic accuracy of the device, but it has been proven that several substances can give rise to selectivity issues and display inaccurate readings. This study aims to investigate the influence of interfering substances, namely ascorbic acid, oxalic acid, and mannose on three commercially available glucometers in Roumania. The devices were tested on aqueous buffer glucose solutions along with different interferents at physiologically relevant concentrations to establish the influence of these substances on the final glucometer readings. We found that ascorbic acid has a significant interference on the studied devices (which to the best of our knowledge has not been previously assessed) – a greater than seven-fold increase from the reference value on all tested devices. Both oxalic acid and mannose exhibited interference on the devices tested at different concentration ranges and were signaled as new potentially interfering substances.
📖 افتح في inklap 🔗 DOI 📮 اطلب بحثاً