This review presents the current known phytochemical constituents of the genus Vepris. The genus is a rich source of alkaloids and limonoids most of which possess the 3, 4- methylenedioxy moieties. They are frequently used as antimalarial in African traditional medicine. The genus Vepris produces a number of metabolites in high quantities whose biological activities including antiplasmodial and antioxidant activities exhibited are discussed. The ethnopharmacology and toxicity of Vepris are also considered.
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