Introduction: Osseointegration is a particular kind of prosthesis that is inserted a short titanium rod or screw into the bone surgically and joined to the prosthetic limb. Experimental part: This study looked at a patient's gait analysis with above-knee amputation wearing an osseointegration prosthesis implant when walking above a force plate. Evaluated the mechanical and fatigue properties of a Ti13Nb13Zr alloy implant. Theoretical part: Drawing and analysis of a femoral bone model with an osseointegration implant using Ansys Workbench 17.2. Results and discussion: The results of the tensile testing showed an ultimate tensile strength of 553 MPa, an average yield strength of 480 MPa, an elongation of 19.66%, and a Young's modulus of 2.73 GPa. Furthermore, a compressive strength of 1010 MPa and a compression yield strength of 700 MPa were found by compression testing. The results of fatigue testing, which were displayed as S-N curves, highlighted the alloy's time-dependent fatigue behavior by showing decreasing fatigue strength with an increase in cycles. The force plate showed a maximum force of 600 N was reported. A strong safety margin was shown by Finite Element Analysis in th
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