Introduction. In the structure of urolithiasis, the predominant number of patients have stones consisting of calcium oxalate. These stones have a dense structure that is not amenable to litholysis and grows quickly. At the moment, there are no medications that can non-invasively relieve patients of this type of stones. In this connection, the main methods of treatment, depending on the size of the stones, are either lithokinetic therapy or surgical treatment. However, stone removal does not eliminate the cause of stone formation, and with this approach, relapse of the disease occurs within 5 years in 30-50% of patients. Today, the search for new approaches and means to reduce the risk of recurrence of calcium oxalate stones does not stop. One of these products is a representative of the Lit-Сontrol® Litura® line from Devicare (Spain) – Litura® Balance. The purpose of this publication is to theoretically substantiate the potential clinical effects of Litura® Balance in the metaphylaxis of calcium oxalate stones. Materials and methods. A literature search and analysis of foreign and domestic literature was carried out using the databases SCOPUS/ScienceDirect, PubMed/MEDLINE, eLibra
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