Background: Occupational health is a neglected public health issue among healthcare workers in developing countries like Yemen and they may expose them to various forms of hazards, which have had negative consequences on their wellbeing and performance at work. Objective: The study aims at exploring the forms of occupational health hazards prevalence and methods to mitigate these hazards among Health Care Workers (HCW) in governmental hospitals in Mukalla city. Methods: It is a cross-sectional study conducted among health workers in the main hospitals in Mukalla city in Hadhramout province in eastern Yemen. The sample size is calculated statistically as 366 workers from different categories including doctors, nurses and lab technicians. A sample of 391 workers were selected randomly who were distributed to be representative and proportional to the size of each professional category. Results: The prevalence of biological hazards among the healthcare workers accounted for 298 (76%) whereas the non-biological hazards accounted for 306 (78%). The most prevalent biological hazards are needle prick injury (80%) followed by exposure to contact with contaminated material (75%), while th
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