Rare Case of Lineage Switch from Acute Myeloid Leukemia to Acute Precursor B Lymphoblastic Leukemia in A 3-Year-Old

Lineage switch defines as an acute leukemia that initially presents with either lymphoid or myeloid phenotype, and then converts to the other one when recurs, while keeping the same genotype. This is associated with poor prognosis and accounts for 0.6% of paediatric leukemia. Hence, we report a rare case of lineage switch from acute myeloid leukemia to precursor B lymphoblastic leukemia in a three-year-old boy.