Profile of Thrombocytopenia in ICU Patients at a Tertiary Care Hospital in Eastern India

Introduction: When severely ill patients are admitted to intensive care units (ICUs), thrombocytopenia— defined as a platelet count below 150,000/µL—occurs frequently. Depending on underlying conditions, drugs, and treatments, its frequency among ICU patients varies greatly, ranging from 8.3% to 67.6%. Aims: To study prevalence, likely aetiologies, pattern among different categories of patients and impact of thrombocytopenia on the 7 days mortality among the critically ill patients in an intensive care unit of a tertiary care hospital in Eastern India. Materials & Methods: This study is a prospective observational study conducted in a single-center setup at Command Hospital (Eastern Command), Kolkata. The study period extends from 1st October 2022 to 31st March 2024, and a total of 150 consecutive patients admitted to the ICU will be included. Result: In our study, majority of the patients were male (64.7%) and most of the patients were from age group 61-80 years (46.7%). 79 patients (52.7%) were admitted with pre-existent thrombocytopenia and 43 patients (28.7%) had developed thrombocytopenia during their hospital stay. The platelet trajectory was found to be biphasic with i