Background: Persistent or recurrent cervical cancer after definitive radiotherapy (RT) or chemoradiotherapy (CCRT) is a foreboding treatment challenge, especially in low- and middle-income settings such as India where late presentation is prevalent. Salvage hysterectomy is a potential curative intervention, but its safety and efficacy are questionable and not proven. Objective: To evaluate clinical outcomes, survival, and surgical feasibility by salvage hysterectomy in women with recurrent or residual cervical cancer after definitive RT/CCRT. Methodology: Retrospective observational study was conducted in the Department of Gynecologic Oncology, Kidwai Memorial Institute of Oncology, Bangalore on 32 patients with FIGO Stage IB2–IIIB cervical cancer treated between the years 2014 to 2019. All the patients underwent prior RT/CCRT and salvage hysterectomy for biopsy-proven residual or recurrence. Demographic, clinical, pathological, and survival information were gathered and analyzed with SPSS v11. Survival was evaluated using Kaplan–Meier and Cox regression models. Results: 32 patients (median age 48.8 years) presented with 71.9% residual disease and 28.1% recurrence. Squamous cell ca
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