Study of Serum Minerals Levels in Hypothyroidism

Background: In light of their direct effect on bone turnover, thyroid function problems, especially hypothyroidism, have drawn more attention recently as a significant source of disruption in mineral metabolism. Many important metabolic pathways that are either directly or indirectly controlled by thyroid hormones require calcium, phosphorus, and magnesium. Research on hypothyroid individuals has yielded conflicting results. Therefore, this study was conducted to assess changes in mineral status by measuring serum levels of calcium, phosphorus, and magnesium in hypothyroid patients and to note the significance of monitoring these levels in subclinical hypothyroid disorders. Methods: In this study 50 known hypothyroid patients on analysis with serum T3, T4 and TSH were included as cases and 50 clinically healthy volunteers included in the control group in age group between 18 and 75 years. Thyroid hormones were measured by Electrochemiluminescence Immunoassay method and Calcium, Magnesium, Phosphorus measured on autoanalyzer. Results: Our study demonstrated normal T3 and T4 level and increased level of TSH in cases suggesting subclinical hypothyroidism. In this study patients sh