Near-infrared fluorescence is increasingly finding utility in surgery. The ease of administering contrast agents, the ability to image in real-time, and the lack of tissue disruption are features of fluorescence imaging which have contributed to its use in the operating room. In this review, we examine fluorescence-guided surgery in the context of sinonasal tumors, evaluate currently available contrast agents and their targets, and discuss future applications of fluorescence in endoscopic sinus surgery.
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