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Basic research in the developmental genetics on the model of tumor growth in higher plants

Lyudmila A. Lutova, Irina E. Dodueva · Ecological genetics · 2023

Today, thanks to use the modern methods of biotechnology, the molecular mechanism underlying different aspects of plant development are started to open up. Along with the traditional methods of genetic analysis, plant developmental genetics actively uses the technics of genetic engineering and “omics” technologies. One of the problems of plant developmental genetics is the study of tumor growth in plants as a model for revealing the mechanisms of systemic control of cell division. Tumor is a pathological structure emerging as a result of uncontrolled proliferation of a group of cells leaving the systemic control of growth rate, cell differentiation and proliferation. Therefore, the elucidation of the mechanisms of tumor formation may help to identify the key regulators of systemic mechanisms controlling cell proliferation and differentiation. Tumor-like structures are found in almost all multicellular organisms, including higher plants. Pathogen-induced tumors, which make up the majority of neoplasms in higher plants, develop under the influence of infectious agents (bacteria, viruses, fungi, nematodes, insects, etc.) which create a niche for their own habitation in the host plant’

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