Scientific and practical evidence of the efficacy of various dentures in orthopedic dentistry in HIV-positive patients

Background: Dental care in HIV-positive patients is a significant problem. The clinical course of the disease, particularly the high risk of infection, along with social and psychological stress, makes the diagnosis and treatment difficult. This necessitates specialized dental care, including the use of modern dentures that improve the functional status of periodontal tissues, increase the stability of masticating pressure, and consider etiopathogenetic mechanisms. Aim: To provide scientific and practical evidence of the efficacy of alternative denture designs in HIV-positive patients with specific clinical and morphological features of periodontal tissue and oral mucosa lesions. Methods: The study included 384 HIV-positive patients (treatment group, TG) and 258 control subjects (control group, CG) who were followed up at the Republican AIDS Center and its Bukhara branch. Of these, 134 TG patients (TG-1), including 68 TG patients (TG-2) and 66 reference group (RG) patients, as well as 38 CG patients, received orthopedic treatment using various types of dentures. TG-2a (n=33) received thermoplastic monomer-free Vertex ThermoSens dentures, whereas TG-2b (n= 5) received Vertex Therm