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Genetic diversity of Telengite and Altai-kizhi populations by markers used in forensic genetics

, Ksenia V. Vagaitseva, Nikita A. Kolesnikov, , Maxim D. Scalin, · Vestnik Tomskogo gosudarstvennogo universiteta. Biologiya · 2025

The need to improve the accuracy of genetic testing in establishing kinship, both in civil cases and when identifying the remains of people after plane crashes, fires, terrorist attacks and other disasters, has led to the development of new methods. One is to expand the panel of used genetic markers by adding highly informative autosomal STR markers. These markers can help identify more closely related individuals, making it easier to determine kinship between parents and children, siblings and stepbrothers. This can be especially useful in difficult cases where traditional methods may not be sufficient. The second is the use of additional markers located on the sex chromosomes. Their features of inheritance simplify the examination of complex cases and provide advantages in the analysis of mixed sample. To correctly use new multiplexes, it is important to have an understanding of the genetic structure of the population from which the DNA profile originates. The level of genetic diversity directly affects the reliability and effectiveness of genetic analysis. In this study, we compared two populations of Southern Altaians using two different systems of genetic markers. These marker

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