Abstract Objectives This study aims to examine the trends and distribution of research areas and methodologies in biochemistry theses over time by performing a bibliometric analysis in the CoHE database and comparing them with PubMed trends. Methods The study includes biochemistry theses from Türkiye spanning 1969 to 2023, totalling 5,543 theses in the CoHe database. Also, the PubMed database is used to compare the world’s and our country’s scientific trends. Google Sheets, AppSheets and Python are used for data analysis. The study employed various bibliometric techniques like performance analysis, cluster analysis, science mapping and co-occurrence analysis. Results Although several diseases exhibited insignificant associations, pregnancy demonstrated a significant positive correlation between CoHE and PubMed trends (ρ=0.455, p=0.0022). The noted negative associations for atherosclerosis (ρ = −0.429, p=0.0041) and hypertension (ρ = −0.470, p=0.0015) suggest that nationa
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