Objectives: To investigate the microtensile bond strength (μTBS) of various adhesive systems (etch & rinse, self-etch, and self-adhesive) for bonding MultiCore Flow and Biodentine at different time intervals. Methods: Sixty pairs of 7x7x3 mm resin-based 3D-printed blocks with a 1x1 mm central tube were used in this study. One side of the blocks was filled with Biodentine, while another side was filled with MultiCore Flow. The materials were bonded using one typeselected from these adhesive systems: ExciTE F DSC (etch & rinse), Multilink N (selfetch), or RelyX U200 (self-adhesive). Each group was subdivided into immediate and delayed groups (n=10). Specimens were subjected to μTBS testing, and failure modes were observed under a stereomicroscope. Two-way ANOVA was used to analyze the influence of time and adhesive system on μTBS. Results: The results revealed that Multilink N group showed significantly higher μTBS in the immediate group compared to the delayed group (p=0.01). When comparing the materials, ExciTE F DSC performed significantly worse than Multilink N (p=0.02) and RelyX U200 (p=0.04) in the immediate group. The predominant failure modes observed under the ster
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