Abstract Background Consultation-Liaison Psychiatry (CLP) services are essential for addressing the psychiatric needs of patients with complex medical conditions in general hospitals. Aims The study aims to characterize profiles of inpatient psychiatry referrals and describe referral patterns and evaluate temporal trends between referrals, patient demographics, and psychiatric and somatic diagnoses. Method Data from January 2020 to December 2023 were collected from a CLP service during and after the pandemic, using psychiatric diagnoses from the International Classification of Diseases, Tenth Revision (ICD-10). Statistical analyses, including interrupted time series analysis with four periods, and including linear and segmented analyses, plus selective use of autocorrelation tests, were conducted to examine referral patterns and their associations with socio-demographic factors. Results 6,105 p
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