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Integrated Genomics and Multi-OMICS in Precision and Personalised Medicine: Emerging New Paradigm for Clinical Medicine

Dhavendra Kumar · Apollo Medicine · 2025

Genomics is one of core components of very basic biological processes of transcription, translation and peptide molecule synthesis, collectively known as the ‘central dogma of life’. This is the basis of multitude of biological sciences with the OMICS suffix, for example, transcriptomics, proteomics, metabolomics and others. Almost all OMIC sciences have direct or indirect bearing on many interrelated biological processes relevant to integrated molecular pathways and systems for all body organs and functioning tissues. The concept of the multi-OMICS medicine is now supported by recurrent outcomes of fundamental and applied life sciences research. The common purpose of multi-OMICS medicine is to deliver the medicine and integrated healthcare as precisely as possible targeted at specific molecular points in an individual patient thus satisfying the basic requirement of personalised medicine. There is growing interest and evidence to integrate multi-OMICS with the traditional ancient medicine systems like Ayurveda. This review provides factual and applied information on multi-OMICS in the context of the evidence-based, ethically sound, precision and personalised medicine.

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