Combined Modality Therapy for Localized Hodgkin’s Disease

Some clinical trials have indicated that combination therapy with intensive radiation therapy followed by chemotherapy significantly prolongs the disease-free interval of patients with Hodgkin’s disease confined .to lymph nodes. The present report updates the results of a small previously published study of combined-modality treatment of stages I and II Hodgkin’s disease. Although patients treated with radiation therapy followed by chemotherapy have the longest median complete remission duration, patients treated with radiation alone have a superior survival rate. Follow-up in this study ranges from 34 to 93 months after the completion of all therapy.