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13/14 Chromosome Translocation and Longevity in Man

G.J. Anday, R.S. Sparkes, H.J. Mindlin · Oncology · 2009

During a cytogenetic study of the aged population (80 years or older) in a Veterans Administration Domiciliary, we found a 90-year-old man whose karyotype showed a 13/14 translocation, evidenced by radioautographic examinations. His karyotype: 45, XY, 13-, 14-, t(13q14q) + was found in blood and skin cultures and in direct bone marrow studies. This man is in good general health; his previous reproductive ability is questionable. The translocation was compatible with its carrier’s longevity. The latter was present in his whole family.

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