Schizogenic cells of the AV3/INO and ER-SV40 lines display numerous aberrations. These cells produce intracells (endogenous microcells), whose morphological type, mechanism of production and fate are described and discussed. The whole population of the ER-SV40 line was abnormal during more than 60 serial subcultures, surviving against any prediction. Asynchronous polykaryocytes, containing regions in different phases of the cell cycle, and cells resembling several lower phylogenetic forms are frequently encountered.
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