Comparison of survival data of 133 patients, treated during the years 1956 to 1964, with a previous series of 135 patients diagnosed during 1933–1955 gave the following results: the 1956–1964 series showed a lower mortality during the first 6–12 months, but the 5-year survival in all stages was lower in the more recently treated series. 61.6% survived 12 months in the 1956–1964 period, as against 53.4% in the 1933–1955 patient group. The corresponding 5-year survival figures were 8.3% (1956–1964) and 21.5% (1933–1955), respectively. Good palliation was achieved by the more intensive radiotherapy and chemotherapy of the more recently treated patients, but the more intensive treatment may lower the host resistance and contribute to the lower survival. Stage of the disease at diagnosis is the most important factor influencing prognosis, but difficulty of staging was emphasized. No correlation between delay and stage of the disease or survival has been found. Histological pattern has probably some bearing on prognosis; solid tumours having a higher malignancy. In the light of the poor treatment results, treatment policy of ovarian cancer has to be reconsidered.
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