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The genetics of the Lp Antigen

C. F. SING, JANE S. SCHULTZ, D. C. SHREFFLER · Annals of Human Genetics · 1974

SUMMARYSeveral genetic models were considered to explain the distribution of qualitatively positive and negative children in 204 Caucasian families. A model which best describes the inheritance of the Lp antigenic expression involves a major genetic locus which distinguishes two overlapping continuously distributed modes of quantitative activity.

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