ABSTRACTThe use of the mouse tail in the study of microvasculature following fractionated radiotherapy is described. Mice are restrained in a perspex housing and mounted on a perspex tray containing slots for individual mice. The mouse restrainer, irradiation set up, and dosimetry are described in detail. Irradiation was carried out using a 4MV Linear accelerator. The technique described here is reproducible. It can be used to study the volume effects in fractionated radiotherapy.
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