Cholangiographic Excretion Studies: Hypertonic Biligrafin Infusion

SummaryA series of matched studies of Biligrafin and bile salt infusion on dogs are reported with isotonic and hypertonic dextrose. Rapid hypertonic infusion produced a lower bile flow rate and higher bile Biligrafin concentration without altering the Biligrafin output. In accordance with previous work it is suggested that this is due to an osmotic effect on plasma and bile.