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Crystallization of Bacteriophage MS2

Willy MIN JOU, Alex RAEYMAEKERS, Walter FIERS · European Journal of Biochemistry · 1979

Crystals of bacteriophage MS2 have been obtained by slowly cooling a 1% virus solution from 23°C to 0°C in the presence of poly(ethylene glycol) 6000. The crystals were colorless, needle‐like, anisotropic and very fragile. Electron microscopic observation of the crystals revealed a two‐dimensional lattice of particles with RNA phage morphology and dimensions. Preliminary X‐ray examination of the crystals confirmed their viral nature.

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