AbstractA new biological activity of bovine parotid protein acting on immunocompetent lymphocytes to lead to polyclonal antibody responses was demonstrated. A significant amount of antibody to SRBC or antihapten antibody to TNP‐SRBC, BPO‐SRBC, or SA‐SRBC was produced in mice by adding the appropriate doses of bovine parotid protein, suggesting that this protein may be a nonspecific B cell activator which acts on the B cells in a similar way as casein or gelatin.
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