ABSTRACT The ethical dilemmas surrounding animal testing in neuroscience are at the forefront of contemporary scientific debate. While animal models have been indispensable in advancing our understanding of complex neural functions and developing treatments for neurological diseases, the field is witnessing rapid innovation in alternative methodologies such as brain organoids, computational models, and artificial intelligence. This essay examines the necessity of animal research, the limitations of current alternatives, and the evolving legal and ethical frameworks that guide responsible neuroscience. By advocating a balanced approach that integrates scientific progress with ethical responsibility, this piece underscores the importance of bridging innovation with compassion in the pursuit of knowledge.
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