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Diabetes‐related outcomes after pancreatic surgery

Cynthia Ying Chian Lee, Barbara Depczynski, Ann Poynten, Koroush S. Haghighi · ANZ Journal of Surgery · 2020

AbstractBackgroundThe development of pancreatogenic diabetes mellitus (PDM) is a common complication post‐pancreatectomy; however, its prevalence has not been described in Australia. We aimed to describe the glycaemic status pre‐ and post‐pancreatectomy, compare patients' clinical characteristics, group according to pre‐ and post‐pancreatectomy diabetes mellitus (DM) status and identify predictors of post‐operative PDM.MethodsWe retrospectively reviewed the medical records of patients admitted for pancreatic resection at a single institution from 2011 to 2017. Post‐operative DM status was determined at the time of discharge or at 30 days post‐operation. Longer term DM onset was as documented in medical record subsequent to admission for pancreatic surgery.ResultsA total of 137 cases were analysed; 13.3% and 24.8% of patients developed post‐operative PDM within 30 days and at median of 1 year (range 1–4 years) follow‐up, respectively. All patients with pre‐existing DM continued to have DM post‐operatively. Patients with pre‐existing DM were older (P = 0.004) and had a family history of DM (P = 0.020); 8.3% of patients who had undergone pancreaticoduodenectomy versus 17.1% of patient

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