Abstract Climate change is modifying weather patterns, producing far-reaching effects on the environment, the economy and society as a whole, endangering global livelihoods, health, food and energy security, and water resources. Europe will not escape its effects, aggravating risks and threats to public health (PH). Today cities are leading the effort to tackle climate change. Cities are embracing digitalization and establishing smart cities (SC). SC should address people mobility, but also the impact of extreme weather phenomena. The degradation of the environment will foreseeably create security and health crisis that could benefit with digital technologies. The development of urban policies should be guided by evidence-based PH practices. The inclusion of PH into the pillars of the SC will contribute toward mitigating PH crises, such as the COVID-19 pandemic. Design Science Research Methodology was used to elicit a Smart Public Health City (SPHEC) framework. A set of PH and SC experts participated in the process, using diabetes as a case study. The European Green Deal served as a blueprint toward a healthier and more sustainable city. The SPHEC framework was defin
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