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DnaA initiator—also a transcription factor

Walter Messer, Christoph Weigel · Molecular Microbiology · 1997

The replication‐initiator protein DnaA is ubiquitous in the eubacterial world. It binds to an asymmetric 9 bp consensus DNA sequence, the DnaA box. Besides its primary function as an initiator, it acts as a transcription factor that represses or activates several genes, or terminates transcription, depending on the location and arrangement of DnaA boxes.

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